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  • OPTION 1: Buy below. Fill out the required  history form (before or after you order)
  • OPTION 2: Buy directly from RVL & Save up to $27% using a subscription. For this option,  fill this form, and you will receive a text and email from RVL to place your order.
Upneeq Size Pack

Skip the trip to the doctor’s office! Your online visit and prescription are included with your purchase if you are deemed a good candidate.

One drop of Upneeq ® per eye, you’ll see a visible difference in as little as 30 minutes, with results lasting 6-10 hours. Does not have to be used daily, but safe to do so! 

How AutoShip Works

  • See results in as little as 5-15 minutes
  • Lasts up to 8 hours
  • Significantly improves upper field of vision
  • No more tired-looking or asymmetrical eyes
  • Non-surgical alternative to blepharoplasty

How to Use


Remove the single-use vial by cutting apart the foil wrapper.


Shake the vial and place one drop of Upneeq® in each afflicted eye once a day, as indicated.


Keep your head tilted back, roll your eyes around, and blink for 15-20 seconds after application to allow the solution to take effect and prevent any from exiting the eye. Take advantage of up to 8 hours of bigger, bolder, brighter eyes!

Key Ingredients

UPNEEQ® (oxymetazoline hydrochloride ophthalmic solution), 0.1% an alpha adrenoceptor agonist. UPNEEQ® is an aseptically prepared, sterile, nonpreserved ophthalmic solution. Each mL of UPNEEQ® (oxymetazoline hydrochloride ophthalmic solution) 0.1% contains 1 mg of oxymetazoline hydrochloride, equivalent to 0.09 mg (0.09%) of oxymetazoline free base. The ophthalmic solution contains the following inactive ingredients: calcium chloride, hydrochloric acid (used to adjust pH to 5.8 to 6.8), hypromellose, magnesium chloride, potassium chloride, sodium acetate, sodium chloride, sodium citrate, and water for injection.

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