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Meet Upneeq®: A Real Eye Opener

Upneeq® is the first and only FDA-approved non-surgical prescription eye drop for acquired ptosis (low-lying lids) that lifts your upper eyelids to open your eyes.

We here at Melamed Eye Care Optometry, are an authorized prescriber and reseller of Upneeq®, a product of RVL Pharmaceuticals. This website is not affiliated with RVL Pharmaceuticals.

    Upneeq®: What is it exactly?

    Upneeq® is the only FDA-approved prescription eye drop for acquired ptosis (low-lying lids) that lifts your upper eyelids to open your eyes

    Upneeq® is also safe and well-tolerated

    • 30-Day Supply. One dose, once daily, or as you need!
    • Results can be seen in as little as 5-15 minutes, with maximum effect in 2 hours.
    • Non-surgical alternative.
    • Gives a youthful look to tired, droopy or asymmetrical eyes.
    • Common side effects (seen in 1-5% of patients) included eye inflammation, eye redness, dry eye, blurred vision, instillation site pain, eye irritation, and headache.

    Upneeq: A Real Eye Opener

    Examples of positive results
    after the first dose of Upneeq

    Actual patient images courtesy of Dr. Robert Schwarcz and Dr. Raymond Douglas. Individual results may vary. The average lift seen in clinical trials was 1 mm.

    Upneeq: A Real Eye Opener

    Millions of people who have acquired ptosis may not even be aware of it

    *Estimate of prevalence was calculated using both U.S. Census data and a published study by Sridharan et al. (1995). The Sridharan study observed a prevalence rate of 11.5% (n=400), which was then applied to the US Census’ projected 2020 population of Americans aged 50+ years.

    • Millions of people over the age of 40 may have acquired ptosis
    • But only 15% have been diagnosed, and even fewer have received any treatment*

    Upneeq: A Real Eye Opener

    Acquired ptosis (low-lying lids) is a common medical condition that:

    • Can develop later in life
    • Affects adults of all ages, but occurs more often aging
    • Usually occurs when the muscles in the eyelid weaken, causing the upper eyelid to droop
    • May be caused by other issues, such as cataract surgery, contact lens wear, or an underlying medical condition. It could also be a sign of a more serious medical condition.

    Delivered to your door

    Upneeq comes in 30-Pack individually wrapped units that are sterile and preservative-free. Each unit contains enough dosage for both eyes, each day.

    The Science Stuff

    The first-in-class treatment called RVL-1201 is an ophthalmic formulation of oxymetazoline, a direct-acting α-adrenergic receptor agonist, which when administered to the eye selectively target Müller’s muscle and elevates the upper eyelid.

    ​Randomized, double-masked, placebo-controlled, multicenter phase 3 clinical trials

    How do I use it?

    One drop, each eye, once a day!

    ​Some use it everyday, others only on special occasions. That’s up to you!

    YOUR VISION IS OUR VISION

    What warnings and precautions are associated with Upneeq?

    • Upneeq is a type of medication that may affect your blood pressure. If you have heart disease, uncontrolled high or low blood pressure, or feel faint at rest or when quickly standing up, you should call your doctor if your symptoms get worse.
    • Patients with reduced blood flow to the brain or heart, or patients who experience eye or mouth dryness due to an immune system disorder (Sjögren’s syndrome), should use care when taking Upneeq. Call your doctor immediately if you feel your symptoms may be getting worse.
    • Upneeq may increase the risk of eye pressure due to fluid buildup (angle-closure glaucoma) in patients with untreated narrow-angle glaucoma. Call your doctor immediately if you feel increased pressure in your eye after using Upneeq.
    • Do not let the tip of the Upneeq vial touch your eye or any other surface. This can help prevent eye injury or contamination. Each Upneeq vial is for one-time use and should be discarded after being used.